Dr. Selva (Sevellaraja Supermaniam), former President of APAGE, a Consultant Obstetrician and Gynecologist at Mahkota Medical Center, Melaka, Malaysia, who is involved in promoting HIFU technology and gynecological endoscopic surgery in Malaysia, shared the influence on fertility of the removal of non-cavity distorting (NCD) intramural fibroids. After showing the classifications of fibroids and demonstrating the pathophysiology that causes subfertility in patients with intramural (NCD) fibroids, Dr. Selva answered the questions on whether intramural (NCD) fibroids cause infertility and whether myomectomy improves pregnancy rates based on several papers. He concluded that myomectomy should not be the first-line treatment in patients with small intramural fibroids, and he provided five non-surgical alternatives including ulipristal acetate, GnRH agonist, atosiban, uterine artery embolisation (UAE), and HIFU, among which HIFU appears to be the most attractive option to shrink small intramural fibroids because it's a noninvasive technique with very few side effects.

Prof. Lian Zhang, Secretary-General of ISMIVS, Director of Chongqing Haifu Hospital and a Chief Editorial Board Member of International Journal of Hyperthermia, gave a speech themed on Pregnancy Outcomes of Patients with Uterine Fibroids or Adenomyosis after HIFU Treatment. He first introduced the working principles and application of HIFU treatment, then he presented pre-and post- HIFU MRI images of some cases with uterine fibroids and adenomyosis. Prof. Zhang Lian mentioned that 293 patients with uterine fibroids and 31 patients with adenomyosis that had been treated with HIFU in Chongqing Haifu Hospital got pregnant and delivered babies after HIFU treatment, and no complications occurred during their pregnancy or delivery. Based on the particular elaboration of several cases he has treated, Prof. Zhang Lian concluded that HIFU treatment was an effective way to help patients who suffered from infertility due to uterine fibroids or adenomyosis, and required more researches to theoretically prove its effectiveness on pregnancy.

Prof. Felix Wong, the Conjoint Professor of the University of New South Wales and Chairman of CA-AMIGO, shared his experience in setting up Hong Kong HIFU Center and some surgery videos of HIFU treatment. With advanced equipment and customized services, Hong Kong HIFU Center has treated 240+ cases in total since September 2019. Prof. Felix Wong also looked back on the development of gynecological surgery from opening surgery to advanced laparoscopic surgery and robotic surgery, and then to focused ultrasound surgery.