Diseases that Harm Require Therapies that Harm Less

---Sir William Osler(1849-1919)
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ISMIVS Newsletter May&June, 2021

Newsletter 2021 May & June
2021年5月及6月简报
About Us 国际微无创医学会简介
The International Society of Minimally Invasive and Virtual Surgery (ISMIVS, previously known as International Society of Minimally Invasive and Noninvasive Medicine) was founded in July 2013 at the gala of the 1st Yangtze International Summit of Minimally Invasive and Noninvasive Medicine in Chongqing, China. ISMIVS envisions to accelerating the progress in minimally invasive and noninvasive medicine by promoting research, education, communication, and international collaboration.
国际微无创医学会(ISMIVS)是在 2013 年 7 月在中国重庆召开的第一届国际微无创医学长江高峰论坛上宣布成立的,旨在通过学术研究、教育、交流以及国际合作加快微无创医学的发展。
Become a member 注册成为会员 >
The Personality in the Medical Education World 医学教育界的大人物

Dr. Olarik Musigavong, M.D
奥拉里克•穆西加翁医生,医学博士

Social Media Team of American Association of Gynecologic Laparoscopist, USA (since 2016)
Assistant Director for Lecturer and Research Affairs of Medical Education Centre (since 2018)
Chairman, Subcommittee Continuing Professional Development, the Royal Thai College of Obstetrcians and Gynecologists (since 2019)
Subcommittee Reproductive Medicine & Gynecological Endoscopy, the Royal Thai college of Obstetrcians and Gynecologist (since 2019)
Thai Medical Council (since 2021)
Best Practice & Research in Clinical Obstetrics and Gynecology (since 2021)
美国妇科腔镜学会(AAGL)社交媒体团队成员(2016 年至今)
医学教育中心讲师和研究事务助理主任(2018 年至今)
泰国皇家妇产科学院持续专业发展小组委员会主席(2019 年至今)
泰国皇家妇产科学院生殖医学委员会、妇科内镜委员会委员(2019 年至今)
泰国医学委员会委员(2021 年至今)
《临床妇产科学之最佳实践与研究》 杂志编辑委员(2021 年至今)

Born in a rural province, Prachinburi, Thailand, Dr. Olarik Musigavong graduated from Faculty of Medicine, Khon Kaen University majoring in Obstetrics and Gynaecology. He also attended professional classes from Reproductive Medicine of Ramathibodi Hospital in coordination with Mahidol University and reproductive surgery training course in Belgium. Furthermore, he received a master degree in the Biotechnology of Human Assisted Reproduction and Embryology from University of Valencia in Spain, and lately became a graduate of doctor's degree in philology and clinical epidemiology of Faculty of Medicine from Thammasart University. His area of interests are reproductive medicine, gynecologic endoscopy, clinical research epidemiology, and health technology startup.
奥拉里克•穆西加翁医生出生在泰国的一个名为巴真武里府(Prachinburi)的农村省份。毕业于孔敬大学医学系,主修妇产科学。还参加了与玛希隆大学合作的拉玛蒂博迪医院生殖医学专业课程和比利时的生殖外科培训课程。此外,获得了西班牙瓦伦西亚大学人类辅助生殖和胚胎学生物技术的硕士学位,最近还获得了塔马萨特大学医学系的语言学和临床流行病学博士学位。兴趣领域包括:生殖医学、妇科内镜、临床研究流行病学、健康科技创业。

Dr. Olarik Musigavong says:"To cure sometimes, to relieve often, and to comfort always are the three main goals of healthcare. From the Hippocrates era until now the healthcare has much improvement. In the next decade, healthcare will move to the next era of IoT, AI, robots, or Quantum computing. The question is how to be a good doctor in the next era. Continuing professional development is the key to become an excellent doctor. The hard skill (medical knowledge, surgical skill, etc.) and soft skills (communication, creativity, collaboration, etc.) are also essential."
奥拉里克•穆西加翁医生如是说道:“有时去治愈、常常去帮助、总是去安慰是医疗保健的三个主要目标。从希波克拉底时代到现在,医疗保健有了很大的改进。在未来十年,医疗保健将进入下一个时代,即物联网、人工智能、机器人、或量子计算时代。如何在下一个时代成为一名好医生?持续的专业发展是成为一名优秀医生的关键。硬技能(医学知识、手术技能等)和软技能(沟通、创造力、合作技能等)也是必不可少的。”

"Moreover, how do we have those skills? Growth mindset and learning skill are the answers. We want to invite every doctor to learn “How to learn” and set up a growth mindset for our patients."
“此外,我们如何拥有这些技能呢?成长思维和学习技能就是答案。我们希望邀请每一位医生学习 "如何学习",并为我们的患者着想建立成长思维。”

News 新闻
How can HIFU help to transform women's healthcare in Africa
高强度聚焦超声(HIFU)可以如何改善非洲妇女的医疗保健状况

Organized by the International Society of Minimally Invasive and Virtual Surgery (ISMIVS), a webinar themed on How can HIFU help to transform women's healthcare in Africa was held on May 28th, 2021, gathering experts from South Africa, Egypt, Nigeria, Ethiopia and Zambia to share latest insights on HIFU treatment.
2021 年 5月 28 日,国际微无创医学会(ISMIVS)举办了主题为“高强度聚焦超声(HIFU)可以如何改善非洲妇女的医疗保健状况”的线上研讨会,集聚了来自南非、埃及、尼日利亚、埃塞俄比亚和赞比亚的多位专家,分享关于 HIFU 治疗的最新见解。

Dr. Raymond Setzen from South Africa shared his experience of HIFU treatment in the large teaching hospital of Chris Hani Baragwanath Hospital in Johannesburg serving for black people. He said that the traditional treatment of fibroids in health care system were usually accompanied by burdens such as lengthy hospital stay, higher costs, overcrowding wards, excessive use of blood, etc. However, with the development of fibroid treatment from hysterectomy to HIFU, hospitals could enjoy the health care benefits of no hospital admissions, no risk of HIV transmission and low risk of complications while patients were also able to enjoy HIFU advantages of quick recovery, no scars and uterus retained. He also mentioned that the recovery time of US-guided HIFU treatment was 1-2 days while the recovery time of hysterectomy was 4-6 weeks. Among the 485 cases he has treated, shrinkage rate found in follow-up after 1, 3, 6 and 12 months were 31%, 52%, 61%, 73% respectively, the average score of QOL increased from around 35 to almost 75 within 24 months after treatment, and the symptom severity score dropped from 60 to below 20. By comparing the pre-HIFU and post-HIFU MR images, he concluded that HIFU was a safe and effective alternative treatment for uterine fibroids in black women, which had great potential for improving women's health and alleviating burdens on his hospital.
来自南非的雷蒙•赛森(Raymond Setzen)医生分享了其在约翰内斯堡 Chris Hani Baragwanath 医院——为黑人患者服务的大型公立教学医院——开展 HIFU 治疗的经验。他指出,传统的子宫肌瘤手术其住院时间较长,费用较高,病房占有率较大,对血液的使用量也较大,对医院造成了不小的负担。随着 HIFU 技术的出现,子宫肌瘤的治疗方式不再局限于子宫切除术,HIFU 治疗无需住院、无需输血,不仅可以缓解医院床位紧张的情况,还可以降低医生由于血液传播感染 HIV 的风险,减少术后并发症;同时,HIFU 治疗能够在保留患者子宫的情况下,极大地缩短患者的恢复时间,不留疤痕。赛森医生还表示,超声引导下的 HIFU 治疗其恢复时间为1-2天,而子宫切除术的恢复时间则为4-6周。赛森医生已应用 HIFU 治疗 485 例子宫肌瘤患者,其中,术后 1 个月、3 个月、6 个月和 12 个月的随访显示肌瘤缩小率分别为 31%、52%、61% 和 73%;术后两年的患者生活质量平均分从 35 分左右上升到了将近 75 分,症状严重程度评分从 60 分下降到不足 20 分。赛森医生展示了多例 HIFU 术前术后的 MRI 影像,并以此总结道,HIFU 治疗黑人女性子宫肌瘤安全有效,对改善女性健康、缓解医院压力具有良好前景。

Prof. Mohamed Hamed from Egypt shared his HIFU experience in HIFU Egypt, the first HIFU center in Middle East and Africa. So far, HIFU Egypt has treated 506 patients, among which there were 308 patients with uterine fibroids and/or adenomyosis and 198 patients with tumors (95 liver HCC, cholangiocarcinoma and metastases, 82 pancreas, 3 liposarcoma, 2 aggressive fibromatosis, 8 benign breast lesions, 3 bone metastases and 5 others). As an interventional oncologist, Prof. Hamed thought it was essential to find a new modality that is noninvasive and valid for difficult tumors. He said that HIFU technology was approved by FDA in the treatment for bone metastases and was also approved outside US for essential tremors, osteoid osteoma, prostate cancer, breast cancer, kidney cancer, liver cancer and pancreatic cancer, which shows the high level of research and proof in this technology. He also shared five factors doctors must master before working with HIFU, including anatomy, positioning, surgical approaches, direction of the power and least power need. After his impressive introduction of HIFU application in different cases, Prof. Hamed concluded that HIFU was a technology of the future and would take a good role in the treatment of benign and malignant tumors.
来自埃及的默罕麦德•哈米德(Mohamed Hamed)教授分享了他在埃及 HIFU 治疗中心开展 HIFU 治疗的经验。作为中东和非洲地区的首个 HIFU 治疗中心,埃及 HIFU 治疗中心目前已治疗 506 例患者,包括 308 例子宫肌瘤和/或子宫腺肌症患者,198 例肿瘤患者(95 例肝细胞瘤、胆管瘤和肝转移瘤、82 例胰腺瘤、3 例脂肪肉瘤、2 例侵袭性纤维瘤、8 例良性乳腺肿块、3 例骨转移瘤以及其他疾病 5 例)。哈米德教授是一位介入肿瘤学专家,他认为针对疑难肿瘤,需要采取无创、有效的新疗法。他指出,目前,HIFU 技术对骨转移瘤的治疗已获得美国 FDA 认证,而其对特发性震颤、骨样骨瘤、前列腺癌、乳腺癌、肾癌、肝癌和胰腺癌的治疗也获得了美国以外地区的广泛认证,这体现了 HIFU技术 的可行性和权威性。此外,哈米德教授还与大家分享了医生开展 HIFU 治疗前必须掌握的 5 大要素,即解剖、定位、手术路径、能量方向和最低能量强度。他还介绍了其应用 HIFU 治疗不同疾病的情况,令人赞叹。哈米德教授表示 HIFU 是一项面向未来的技术,将在良恶性肿瘤的治疗中发挥良好作用。

Based on his clinical practice in gynecology, Dr. Abayomi Ajayi from Nigeria shared his thoughts on the clinical impact of HIFU on gynecology in Africa. He mentioned a survey by a tertiary health institution in South-south Nigeria, which showed that uterine fibroids accounted for 7.1% of gynaecological admissions and 21.2% of major gynaecological surgeries, and that most of the cases were seen in 30-39 age group and those with nulliparous status. And in a study of over 900 infertile black African women who had hysteroscopy between 2005 and 2014, open myomectomy was found as a significant factor for intrauterine adhesions. Consider the huge service gap and knotty post-operative complications, the HIFU technology rose in response in Africa. Dr. Ajayi shared a group of statistics in an IDEAL Study that among 1353 women received HIFU, 472 hysterectomies and 586 myomectomies, major adverse events occurred in 0.2% of HIFU and in 12.6% of surgical cases, which showed a significant less morbidity of HIFU than surgery. Dr. Ajayi concluded that HIFU was effective, safe with less complications than surgical treatment.
来自尼日利亚的阿巴约米•阿贾伊(Abayomi Ajayi)医生结合自己的妇科临床实践,就 HIFU 治疗对非洲地区妇科发展的影响发表了看法。阿贾伊医生提到,根据南尼日利亚(南)某卫生机构的调查,子宫肌瘤患者占妇科疾病患者的7.1%,子宫肌瘤治疗占主要妇科手术的21.2%,且子宫肌瘤多发于 30-39 岁年龄段女性和未生育女性。另外,根据一项针对 2005 年至 2014 年间接受宫腔镜检查的 900 多名不孕不育非洲黑人妇女开展的研究调查,开腹子宫肌瘤剔除术是导致宫腔粘连的一个重要因素。考虑到巨大的医疗服务缺口以及棘手的术后并发症,HIFU 技术在非洲地区兴起。阿贾伊医生还分享了一项 IDEAL 研究公布的统计数据:1353 例患者接受HIFU治疗,472 例患者接受子宫切除术,586 例患者接受子宫肌瘤剔除术,HIFU 组严重不良反应发生率为0.2%,而手术组的不良反应发生率为12.6%,这表明 HIFU 治疗可以大大降低不良反应发生率。阿贾伊医生总结道 HIFU 治疗安全有效,并且并发症发生率低于手术治疗。

Dr. Andrei Klimash from Russia mainly introduced the Silk Road General Hospital in Addis Ababa, Ethiopia in the following eight aspects: 1. healthcare services; 2. diagnostic devices; 3. operation theatre; 4. neurological and neurosurgical care; 5. orthopedic care; 6. surgical, gynecological and urological care; 7. general care; 8. professionals and team members. The Silk Road General Hospital is working on the HIFU project, aiming to bring the HIFU treatment to the patients in Ethiopia and clinical training to local doctors.
来自俄罗斯的安德烈•克里玛什(Andrei Klimash)医生主要从以下八个方面介绍了埃塞俄比亚亚的斯亚贝巴丝路综合医院的相关情况:1)医疗服务;2)诊疗设备;3)手术室;4)神经及神经外科;5)骨科;6)外科、妇科和泌尿科;7)综合护理;8)专家团队。丝路综合医院正着手搭建 HIFU 治疗中心,以便从治疗端惠及埃塞俄比亚患者、从临床培训端惠及埃塞俄比亚医生。

Dr. Muzaza A. M. Nthele, Counselor-Health, Embassy of Zambia in China, shared his second trip to Chongqing Haifu Medical and introduced the Zambian expert team. During his visit to Chongqing, Dr. Muzaza got to know the noninvasive HIFU technology using non-ionizing ultrasonic waves to heat or ablate tissue and decided to bring it to Zambia to treat the patients with uterine fibroids. He mentioned that open surgery was widely used in Zambia, but may easily cause blood shortage supply and affect fertility. Dr. Muzaza believed that the import of the HIFU technology would allow doctors in Zambia to treat uterine fibroids without the need for blood or competing with other urgent cases. He hoped to create hunger in the Zambia team for HIFU technology through this webinar.
赞比亚共和国驻华使馆(卫生)参赞木咋咋博士在会上分享了他在重庆的第二次海扶之旅,并为大家介绍了来自赞比亚的专家团队。在此次到访中,木咋咋博士实地观摩手术,了解了非电离超声波加热或消融靶组织的无创 HIFU 治疗技术,并且决定将 HIFU 技术引入赞比亚治疗子宫肌瘤患者。他提到,赞比亚多采用开腹手术,但开腹手术容易造成血液供应不足、影响生育等问题。HIFU 技术的引进不仅可以帮助赞比亚医生解决子宫肌瘤治疗过程中血液供应的问题,还可以缓解医院的接诊压力。木咋咋博士希望通过本次研讨会,激发赞比亚团队对 HIFU 技术的兴趣。

Notice通知
APAGE-ISMIVS HIFU Series Webinars 2021: HIFU and Fertility, Potential or Not?
2021年国际微无创医学会(ISMIVS)与亚太妇产科内视镜暨微创治疗医学会(APAGE)联合会议
暨2021年高强度聚焦超声(HIFU)系列线上研讨会(AIH)

To foster academic exchanges in the new field of minimally invasive and noninvasive surgeries and deliver scientific and educational dialogues across continents, the Asia-Pacific Association for Gynecologic Endoscopy and Minimally Invasive Therapy (APAGE) and the International Society of Minimally Invasive and Virtual Surgery (ISMIVS) have been co-organizing APAGE - ISMIVS HIFU (AIH) Webinar Series 2021, which is themed on HIFU and Fertility, Potential or Not? and consists of 4 episodes starting from July to December, 2021.
为促进微无创手术领域的学术交流,国际微无创医学会(ISMIVS)联合亚太妇产科内视镜暨微创治疗医学会(APAGE)将于 2021 年 7 月至 12 月举办 4 场高强度聚焦超声(HIFU)线上系列研讨会。来自世界各地的医学专家将围绕“HIFU 与生殖:潜力与否”的主题为大家带来一场科学与教育的盛宴。

Follow us on Facebook and get free registration for the following episodes:
关注我们的Facebook账号,免费注册本系列研讨会:
International Society of Minimally Invasive and Virtual Surgery | Facebook
Looking forward to seeing you!
期待您的参与!
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ISMIVS launching its online training program
国际微无创医学会培训课程上线中

The International Society of Minimally Invasive and Virtual Surgery is pleased to announce the availability of a series of online training courses on the clinical application of noninvasive focused ultrasound therapy. A variety of courses related with ultrasound-guided high intensity focused ultrasound (HIFU) ablation of uterine fibroids will enlighten doctors about the physics and biological effect of HIFU, case screening, clinical protocol, anesthesia plan, nursing care, etc. In the meantime, more courses on focused ultrasound therapy of other diseases will be uploaded in the future, please follow us on www.ismivs.org for what you are interested in.
国际微无创医学会很高兴向大家宣布:我们的线上培训课程开始正式上线。课程将涵盖超声引导的高强度聚焦超声(HIFU)消融子宫肌瘤的物理学基础和生物学效应、病例筛选、临床方案、麻醉方案以及临床护理等。同时更多聚焦超声无创治疗其他疾病的课程将陆续上线,欲了解更多,请关注我们的官方网站 www.ismivs.org
The training courses are accessible only to part of ISMIVS members.
培训课程仅向部分国际微无创医学会会员开放。
Training Course Introduction: MRI Features of Pelvic Diseases
培训课程介绍:盆腔疾病的磁共振影像特征
This lecture shall introduce the MRI features of pelvic diseases, which consists of six parts: 1. the principles of magnetic resonance imaging (MRI); 2. charateristics of MR images; 3. MR signals of different human tissues; 4. MRI-based diagnosis of benign and malignant pelvic diseases; 5. prediction of HIFU efficacy based on pre-HIFU MR images; 4. evaluation of HIFU efficacy based on post-HIFU MR images.
本课程介绍了盆腔疾病的磁共振影像特征,主要包括以下六个方面:1. 磁共振成像原理;2. 磁共振图像特点;3. 不同人体组织的磁共振信号;4. 盆腔良恶性疾病的诊断;5. 术前利用磁共振图像预测疗效;5. 术后利用磁共振图像评估治疗效果。

Become a member >
申请成为会员 >
To apply for the training courses,
please contact the ISMIVS Secretariat
jennyzhang@isminim.org
申请线上课程学习,
请联系国际微无创医学会秘书处
jennyzhang@isminim.org

Tech Update 微无创技术新进展
A journey from learning a noninvasive high-intensity focused ultrasound surgical treatment for gynecological diseases to providing high-intensity focused ultrasound services in Hong Kong
从学习高强度聚焦超声手术治疗妇科疾病的无创技术到在香港提供高强度聚焦超声服务的历程

This paper introduces a Hong Kong doctor team's journey of learning high-intensity focused ultrasound (HIFU) ablation treatment for gynecological diseases in mainland China from April 2019 to June 2019. The procedures of HIFU ablation for fibroids, adenomyosis, and other gynecological diseases are described. After completing their training, the doctors have established an outpatient HIFU clinic and provided HIFU ablation treatment in Hong Kong. This paper describes their early experience in providing HIFU services.
本文介绍了香港医生团队于 2019 年 4 月至 6 月到访中国大陆,学习高强度聚焦超声(HIFU)消融治疗妇科疾病的过程,讲述了 HIFU 消融子宫肌瘤、子宫腺肌症和其他妇科疾病的原理、临床应用。完成培训后,医生团队在香港建立了一家 HIFU 门诊诊所,提供 HIFU 消融治疗。本文介绍的是他们在提供 HIFU 治疗服务的早期经验。

From October 2019 to December 2020, they treated 147 patients successfully as a day-surgery procedure. Of all the 147 patients, they only encountered three mild postoperative complications such as skin burn, back pain, and temporary sciatic nerve impairment. They all recovered well with conservative management without medication.
从 2019 年 10 月至 2020 年 12 月,他们采用日间手术模式,成功治疗了 147 例患者。在这 147 例患者中,只有 3 例患者出现轻度术后并发症,如皮肤烧伤、背部疼痛和暂时性坐骨神经损伤,但无需药物治疗,仅经保守治疗后,均恢复良好。
Read More >
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A suturing method without exposure of barbs on the wound surface using a unidirectional barbed monofilament absorbable suture (STRATAFIX™) in laparoscopic myomectomy:
A feasibility study
一项关于腹腔镜下子宫肌瘤剔除术缝合方法的可行性研究:
使用可吸收的带有单向倒钩的单丝缝合线不暴露伤口表面倒刺(STRATAFIX™)

In this retrospective study, 26 women underwent laparoscopic myomectomy (LM) for symptomatic uterine fibroids. The operative time, amount of blood loss, and number of threads used were compared between conventional suture group (n=13) and barbed suture group (n=13).
这是一项回顾性研究。研究对象为26名有子宫肌瘤症状的患者接受了腹腔镜剔除肌瘤的治疗。比较了传统缝合组(n = 13)和倒刺缝合组(n = 13)的手术时间、出血量和缝线数。
This study showed that, when compared with conventional suturing, the new suturing method with a unidirectional barbed suture was feasible for LM. The new suturing method was superior in terms of shortening operative time and reducing the amount of blood loss; moreover, it was not inferior to the conventional method in terms of cost.
本研究表明,与传统缝合方法相比,腹腔镜下子宫肌瘤剔除术使用单向倒钩缝合线的缝合方法是可行的。这一新缝合方法在缩短手术时间、减少出血量方面具有优越性,而且在成本上也不逊色于传统方法。
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International Guidelines on Gynaecological Endoscopy  国际妇科腔镜指南
Joint Statement on Minimally Invasive Gynecologic Surgery during the COVID-19 Pandemic
关于COVID-19大流行病期间微创妇科手术的联合声明


The American Association of Gynecologic Laparoscopists (AAGL) along with the American Urogynecologic Society, International Gynecologic Cancer Society, Society of Gynecologic Oncology and Society of Gynecologic Surgeons made the recommendation in a joint statement that nonessential surgical care should be suspended during the Covid-19 pandemic and if the surgery is essential, it should be carried out following amended treatment protocols under the pandemic. In addition, recommendations for best practice are listed when laparoscopy or robot-assisted laparoscopy is performed, such as:(1) Employ electrosurgical and ultrasonic devices in a manner that minimizes the production of plume, with low-power setting and avoiding long desiccation times. (2) A laparoscopic suction may be used to remove surgical plume and desufflate the abdominal cavity; do not vent pneumoperitoneum into the room., etc.
美国妇科腹腔镜协会联合美国妇科泌尿学会、国际妇科癌症学会、妇科肿瘤学会、妇科外科学会的联合声明中建议到,在疫情状况下应该暂停所有非紧急手术,如果有必须治疗的手术,需要遵循一些治疗原则,针对实施腹腔镜或机器人辅助腹腔镜时补充提出了最佳实践建议,例如采用电外科和超声波设备,以尽量减少烟羽的产生,低功率设置,避免长时间干燥;采用腹腔镜吸引术清除手术羽流,并对腹腔进行去填塞;不要将气腹排出室内等等。
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